Cell-Penetrating Peptides - Design, Development and Applications
Verlag | Wiley-VCH |
Auflage | 2023 |
Seiten | 416 |
Format | 19,5 x 2,4 x 25 cm |
Gewicht | 952 g |
Artikeltyp | Englisches Buch |
ISBN-10 | 352735011X |
EAN | 9783527350117 |
Bestell-Nr | 52735011A |
The modern reference on the rational design and development of cell-penetrating peptides (CPPs) for use in cellular delivery of drugs and various other cargoes.
Inhaltsverzeichnis:
IntroductionPART 1: DESGIN OF CPPSClassification of cell-penetrating peptidesArginine-rich cell-penetrating peptides: recent advances of design and applications for intracellular deliveryCationic cell-penetrating peptidesAmphipathic cell-penetrating peptidesHydrophobic cell-penetrating peptidesFoldamersPART 2: MECHANISM OF CPPSPeptide Structure: Electrophysiological analysis, nuclear magnetic resonance analysis, and molecular dynamics simulation of direct penetration of cell-penetrating peptides through bilayer lipid membranesCellular uptake mechanisms of arginine-rich cell-penetrating peptidesEndosomal escapePharmacokinetics of therapeutic and diagnostic agents conjugated with cell-penetrating peptidesPART 3: DELIVERY TOOLSDrug deliveryPeptide & protein deliveryCell-penetrating peptides for nucleic acid deliveryPPMOs: a case study for cell-penetrating peptide applicationCell penetrating peptide-conjugated polymer micelles for pDNA/siRNA deliveryLipid-based nanoparticles using cel l-penetrating peptidesPART 4: APPLICATIONSCell-penetrating peptides as tools to facilitate oral delivery of biopharmaceuticalsIntranasal deliveryClinical trialsApplications in plants