Fast Facts for Patients: Thrombotic Thrombocytopenic Purpura - Prompt Action Saves Lives
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78,99 €
| Verlag | Karger |
| Auflage | 2022 |
| Seiten | 32 |
| Format | 15,0 x 0,2 x 21,0 cm |
| Gewicht | 68 g |
| Artikeltyp | Englisches Buch |
| ISBN-10 | 3318070831 |
| EAN | 9783318070835 |
| Bestell-Nr | 31807083A |
Thrombotic thrombocytopenic purpura (TTP) is a rare disorder of the blood coagulation system. In most cases, a lack of the ADAMTS13 enzyme leads to an accumulation of ultra-large von Willebrand factor molecules in the plasma which, in turn, initiate the formation of microscopic thromboses in small blood vessels. TTP is a medical emergency. Timely diagnosis and urgent and effective management are vital - mortality in those untreated is in the region of 90%.The understanding of TTP pathogenesis has increased markedly in recent decades. It is now known that TTP is acquired (immunemediated) or congenital, and that the most common type - the acquired form - predominantly affects women in their 40s. It is also clear that the prompt delivery of plasma exchange saves lives. 'Fast Facts: Thrombotic Thrombocytopenic Purpura' sets out, in a clear and accessible format, the steps to suspecting, diagnosing and treating this potentially devastating disease. These steps are complemented by clea r descriptions of the disease mechanism and epidemiology. Differential diagnosis, which is of the utmost importance for this disease, is explored in detail.
