Reaction Mechanisms in Organic Chemistry

Understanding organic reaction mechanisms is the key for understanding organic chemistry. That is the concept of this unique textbook which supports the students perfectly to understand organic chemistry in a very comprehensive way. Includes a problem & solution section, too.

Inhaltsverzeichnis:

BASIC CONCEPTSCovalent Bonding and HybridizationElectrophiles and NucleophilesInductive and Mesomeric EffectsFormal Charge And Oxidation NumberAcids And BasesReaction Kinetics And Energy Diagrams NUCLEOPHILIC SUBSTITUTION REACTIONSUnimolecular Substitution Reactions SN1Stereochemistry in SN1 ReactionsOptical ActivityBimolecular Substitution Reactions SN2Stereochemistry of SN2 ReactionsNucleophilic Substitution On Allylic Systems: Allylic RearrangementInternal Nucleophilic Substitution Reaction SNiNeighboring Group Participation in Nucleophilic Substitution ReactionsAmbident NucleophilesVarious Nucleophilic Substitution ReactionsELIMINATION REACTIONSUnimolecular Elimination Reactions, E1Bimolecular Elimination Reactions, E2 Unimolecular Conjugate BaseHalogene EliminationHofmann Elimination: Quaternary Ammonium SaltsPyrolitic Eliminations: Intramolecular cis-Elimination ReactionsElimination at the Bridgehead: Bredt?s RuleADDITION REACTIONSHalogen Addition To Double Bonds: Halogena tionAddition of Hydrogen Halides to Double Bonds: Markovnikov?s RuleAnti-Markovnikov Addition of Hydrogen Halides to AlkenesAddition of Water to AlkenesOxymercuration and DemercurationHydroboration of Alkenes: Anti-Markovnikov HydrationEpoxidation of the AlkenesVicinal cis-DihydroxylationDihydroxylation via PIFAEnzymatic DihydroxylationOzonolysis: Oxidative Cleavage of AlkenesReduction of AlkenesAddition to Conjugated DienesCARBONYL COMPOUNDS AND THEIR REACTIONSStructure-Reactivity RelationshipsReactions of Carbonyl CompoundsCarbonyl Addition ReactionsUmpolung: Polarity Inversion of Aldehyde Carbonyl GroupReactions of Aldehydes and Ketones with AminesReduction of Carbonyl GroupsReaction of Carbonyl Groups with Organometallic CompoundsReaction of Carbonyl Groups with YlidesPhosphonium Ylides and Wittig ReactionReactivity of alpha-Carbon Atom Keto-Enol TautomerismProton-Deuterium Exchange alpha-Halogenation of Ketones and Aldehydes: Haloform Reaction Hell-Volhard-Zelinsky Reactiona lpha-Alkylation of Carbonyl CompoundsEnolates Derived from 1,3-Dicarbonyl Compounds Condensation Reactions of Carbonyl Compounds Typical Reactions of Acids and Esters TransesterificationAROMATIC COMPOUNDSStructure of Benzene Aromatic, Antiaromatic, and Nonaromatic CompoundsDetermination of the Molecular orbitals of Aromatic CompoundsWhat are the criteria for aromaticity? How does one quantify aromaticity?HomoaromaticityMöbius AromaticityAromatic IonsAnnulenesAromaticity in Fused SystemsAromaticity in Heterocyclic CompoundsElectrophilic Aromatic Substitution: Chemistry of BenzeneReactivity of Monosubstituted Benzene DerivativesDirecting Effects of Substituents: Activating Groups Electrophilic Aromatic Substitution on Disubstituted BenzenesFunctionalization of the Side Chain Substituents of Benzene Nucleophilic Aromatic Substitution ReactionsPolycyclic Aromatic CompoundsBenzenoid Aromatic CompoundsREACTIVE INTERMEDIATESCarbocationsCarbanionsCarbenesNitrenesRadicalsSinglet OxygenPER ICYCLIC REACTIONSWoodward Hoffmann Rules Frontier Orbitals Electrocyclic Reactions Application of Woodward Hoffmann Rules Correlation Diagrams Cycloaddition Reactions Secondary Orbital Interaction Orbital Coefficients Sigmatropic ReactionsCope and Claisen RearrangementCARBON-CARBON (C-C) COUPLING REACTIONSHistoryMizoroki-Heck Coupling ReactionStille-Coupling Reaction Suzuki-Miyaura Coupling Reaction Negishi-Coupling ReactionSonogashira-Coupling Reaction Kumada-Coupling Reaction Hiyama-Coupling Reaction Hiyama-Denmark CouplingBuchwald-Hartwig CouplingTsuji-Trost Coupling Palladium-catalyzed Carbonylation ReactionsCarbonylative Coupling Reactions with Organometallic ReagentsMo(CO)6-Mediated Carbonylation