Urinary System

A complete update on the safety testing of foods, drugs, and chemicals in laboratory animals, featuring: - a thorough review of each subject area with extensive revision in line with new information and concepts - electron micrographs in exquisite detail to illustrate results of recent research - the effects of many carcinogens described succinctly and illustrated in detail - neoplasms described in detail and compared with natural and induced tumours in other species - standardised nomenclature. Of interest to those interested in the many applications to human patients, Urinary System: - facilitates uniform interpretation of bioassay results world-wide - provides a basis for understanding mechanisms involved in the functions and malfunctions of the most minute, but important structures of the kidneys - explains the functional significance of details by identifying the composition of structures at the molecular level. Forming a solid basis for understanding the causes and effects o f disease of the urinary system, this is essential reading for pathologists, toxicologists, regulatory agencies, and all those involved in carcinogenicity and toxicity studies.

Inhaltsverzeichnis:

The Kidney.- Anatomy, Histology, Ultrastructure.- Anatomy, Cytology, Ultrastructure Nephron and Collecting Duct Structure in the Kidney, Rat.- Unique Features of Anatomy, Histology, and Ultrastructure, Kidney, Mouse.- Neoplasms.- Renal Carcinogenesis, Rat.- Oncocytoma, Kidney, Rat.- Renal Cell Adenoma and Carcinoma, Rat.- Mesenchymal Tumor, Kidney, Rat.- Nephroblastoma, Kidney, Rat.- Lipomatous Tumors, Kidney, Rat.- Adenoma, Adenocarcinoma, Kidney, Mouse.- Adenoma, Kidney, Syrian Hamster.- Adenocarcinoma, Kidney, Syrian Hamster.- Angioma, Angiosarcoma, Kidney, Syrian Hamster.- Hereditary Renal Cell Adenoma and Carcinoma, Rat.- Estrogen-Induced Malignant Tumor, Kidney, Golden Hamster.- Non-Neoplastic Lesions.- Immune Mechanisms in Injury to Glomeruli and Tubulointerstitial Tissue.- Spontaneous Renal Amyloidosis, Syrian Hamster.- Chronic Progressive Nephropathy, Rat.- Infarction, Kidney, Rat, Mouse.- Interstitial Nephritis, Mouse.- Suppurative Nephritis, Pyelonephritis, Mouse.- Supp urative Nephritis, Pyelonephritis, Rat.- Chloroform Nephrosis, Male Mouse.- Acute Tubular Lesions, Kidney, Rat.- Juxtaglomerular Cell Hyperplasia, Induced, Laboratory Animals.- Daunomycin-Induced Nephropathy, Rat.- Effect of Experimental Diabetes Mellitus, Kidney, Rat.- Experimental Renal Effects of Analgesics, Rat.- Diphenylthiazole-Induced Renal Cystic Disease, Rat.- Congenital and Inherited Disorders.- Spontaneous Hydronephrosis, Rat.- Nephronophthisis, Mouse.- Parasitic Infections.- Klossiellosis, Kidney, Mouse, Rat.- Renal Pelvis, Ureters, Urinary Bladder, Urethra.- Histology, Ultrastructure.- Histology, Ultrastructure, Urinary Tract, Mouse.- Transitional Epithelium, Bladder, Rat.- Neoplasms.- Hyperplasia, Urinary Bladder, Rat.- Classification and Differential Diagnosis of Neoplasms, Urinary Bladder, Rat.- Carcinogenesis, Urinary Tract, Rat.- Transitional Cell Carcinoma, Bladder, Rat.- Transitional Cell Carcinoma, Urinary Tract, Mouse.- Papilloma, Urinary Bladder, Rat.- Squam ous Cell Carcinoma, Urinary Bladder, Rat.- Adenocarcinoma, Urinary Bladder, Rat.- Undifferentiated Carcinoma, Urinary Bladder, Rat.- Induction of Cancer in the Rat Bladder: Pathogenesis, Role of Cell Proliferation, and Relevance to Human Disease.- Submucosal Mesenchymal Tumor, Urinary Bladder, Mouse.- Non-Neoplastic Lesions.- Calcium Oxalate Urolithiasis, Rat.- Urinary Glycoproteins as Modulators of Calcific Nephrolithiasis.- Phosphate Urolithiasis, Rat.- Urologic Syndrome, Mouse.- Parasitic Infections.- Trichosomoides crassicauda Infection, Urinary Bladder, Rat.