Classics in Stereoselective Synthesis
| Verlag | Wiley-VCH |
| Auflage | 2008 |
| Seiten | 632 |
| Format | 19,8 x 25,9 x 4,0 cm |
| Gewicht | 1586 g |
| Artikeltyp | Englisches Buch |
| ISBN-10 | 3527324526 |
| EAN | 9783527324521 |
| Bestell-Nr | 52732452A |
Die wichtigsten und nützlichsten Methoden der modernen stereoselektiven Synthese sind in diesem Band zusammengefasst. Viele anschauliche Beispiele für die Darstellung von Wirkstoffen und Naturstoffen regen zur gezielten Abwandlung und Integration in eigene Synthesewege an. Dabei geht es den Autoren weniger darum, das Gebiet in seiner Gesamtheit darzustellen; vielmehr versuchen sie, die wirklich grundlegenden Ansätze auszuwählen, die jeder organische Synthesechemiker kennen und anwenden sollte.
Klappentext:
This book provides a noteworthy compilation of the groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field. The work also features illustrative examples of drug and natural product syntheses, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the construction of stereochemically complex structures.
From the contents:
"Macrocyclic stereocontrol
"Carbonyl addition reactions
"alpha-Functionalization of enolates
"Aldol and allylation reactions
"Chiral acetals
"Alkene hydroboration, reduction, and oxidation
"Additions to C=N bonds and synthesis of amino acids
"Conjugate additions
"Chiral carbanions
"Metal-catalyzed allylations
"Cyclopropanations and CH-insertion r eactions
"Sigmatropic rearrangements
"Diels-Alder and hetero-Diels-Alder reactions
"[3+2]- and [2+2]-cycloaddition reactions
Rezension:
"The book provides a collection of classic methods for stereoselective synthesis that have been developed over the past two decades - methods that should be at the command of every modern practitioner of synthetic organic chemistry." (Booknews, 1 April 2011)